Personal Profile
Dr Stephen Karp graduated from the University of London with a First Class Honours Degree BSc) in Pharmacology from Kings College in 1976 and with an MBBS degree in Medicine with a Distinction in Surgery from Westminster Medical School in 1979. He trained in General Medicine at Hammersmith Hospital, Whittington Hospital, National Hospital Queen Square and Northwick Park Hospital and in Clinical Oncology at the Middlesex and Mount Vernon Hospitals. He was appointed a Consultant in 1990 working in the NHS until 2017 at North Middlesex University Hospital and at Royal Free Hospital. He is also an Honorary Consultant at University College London Hospitals and was an Assistant Professor of Medicine at St George’s University School of Medicine and Honorary Clinical Senior Lecturer in Oncology at UCLH.
Dr Karp’s general training included cardiology, renal medicine, chest medicine, care of the elderly, neurology and gastroenterology. On his appointment in 1990 he treated a wide range of tumour types eventually specialising in cancers of the breast, urology and gastrointestinal cancer.
Throughout his career Dr Karp was involved in the training of Junior Doctor Trainees in Oncology as well as GPs, Nurses and Pharmacists.
Dr Karp was involved in many clinical trials in Oncology. Dr Karp led the Royal College of Radiologists COIN project (Clinical Oncology Information Network) which produced 6 national cancer guidelines including breast and prostate cancer and designed and tested clinical workstations for oncology. He was heavily involved in clinical audit and evidence-based medicine projects.
After retirement from the NHS Dr Karp is now mainly treating Breast & Prostate Cancer.
Dr Karp has extensive experience of the use of chemotherapy, which nowadays includes targeted drugs, immunotherapy, as well as hormonal therapy including the latest advanced agents such as CDK 4/6 inhibitors for breast cancers and advanced androgen blocking agents for prostate cancer, such as Abiraterone, Enzalutamide, Apalutamide, etc. Where appropriate gene profiling is used to better select patients for systemic therapy and in advanced cancer liquid biopsies which yield genomic profiling or tumour mutation profiling might be used.
Dr Karp also has access to advanced radiotherapy including SABR and Cyberknife and advanced radio-isotope therapies for breast and prostate cancer.
• Management of localised and metastatic Breast Cancer
• Management of localised and metastatic Prostate Cancer
• External beam radiotherapy
• VMAT/Rapid Arc/ Intensity-modulated radiotherapy
• SABR
• Cyberknife
• Chemotherapy
• Hormone treatment
• Proton Beam Radiotherapy
